On freshly cleansed face, neck and décolleté. Apply 2 pumps of serum and massage into the treatment area. Follow with serum or creams (optional) but R Pur may be used as a stand alone product. Re-apply product every night until finished (i.e. to the bottom of the bottle). As part of an anti-aging program, this may be repeated up to 2-3 times per year (i.e. every 4-6 months).