How Can Glutathione and Vitamin C Benefit My Skin?

How Can Glutathione and Vitamin C Benefit My Skin?

September 12, 2025

There is a lot more information available today about how environmental stressors affect our skin’s appearance as we age, and one of the biggest (and often overlooked) culprits is UV damage. While we all know about the importance of SPF, glutathione and Vitamin C are two other ingredients that can help combat the aging effects of UV and other environmental stressors. 

Below, we’ll discuss these skincare ingredients, their benefits, and how pairing them together can help keep your skin looking radiant, youthful, and free from intense sun damage. We’ll also discuss where to find the best Vitamin C and glutathione serum from Isomers Skincare.

What Glutathione Can Do

Glutathione is a naturally occurring antioxidant and peptide in the skin. This ingredient contains three amino acids: cysteine, glutamic acid, and glycine, which help reduce visible signs of discoloration in the complexion. 

Glutathione protects the skin from oxidative stress and environmental damage, neutralizes free radicals, and overall works to promote a more even, radiant skin tone. This ingredient is particularly effective for adults 35 plus, aiming to ward off issues like dark spots and hyperpigmentation, a common symptom of aging in the skin. 

How Vitamin C Works in the Skin

Vitamin C (Sodium Ascorbyl Phosphate) is an indispensable vitamin for your skin that offers a lot of benefits. One of its key benefits is enhanced protection against the sun and UV damage. While you can’t replace Vitamin C with SPF and its UV-absorbing capabilities (which you should always apply, even during the winter), Vitamin C can help protect the skin from the harmful effects of UV rays caused by free radicals.  

Other benefits of Vitamin C include:

  • Brightens the skin by reducing dark spots and promoting an even skin tone
  • Boosts collagen production
  • Enhances skin firmness and elasticity to help minimize the appearance of wrinkles and fine lines

The Benefits of Pairing Vitamin C and Glutathione Together

So, what is the link between Vitamin C and glutathione? They are clearly very effective on their own steam, so how can your skin benefit by pairing them together? 

Combining these two antioxidants helps increase the efficacy of their shared strengths to tackle free radicals, reduce inflammation, and combat oxidative stress. In addition to their combined antioxidant properties, pairing Vitamin C with glutathione enhances its effectiveness.

Vitamin C can remove free radicals faster than glutathione, allowing the latter to preserve its levels and let its other strengths work into the skin. Vitamin C also helps regenerate glutathione back to its active form to enhance its power and long-term effects, while glutathione protects cells from oxidative damage by recycling Vitamin C.

Overall, if you want to increase glutathione's effectiveness, applying it with Vitamin C can help you see better, more tangible results from your skincare routine. With consistent application, some benefits include reduced visible signs of aging, a more even skin tone, and enhanced protection from sun damage. 

Vitamin C and Glutathione Serum from Isomers Skincare

You can find effective, results-driven glutathione serum and Vitamin C-based products from Isomers Skincare. For over 40 years, we have been Canada’s leading developer of science-forward skincare products. You can find the following items in our Shop:


Not sure which products will work best for your skin type? Take our Skincare Quiz to learn about how you can effectively target discolouration, sun damage, fine lines, wrinkles, and more with our product recommendations.