How Matrixyl-4 Peptides Support Anti-Aging

How Matrixyl-4 Peptides Support Anti-Aging

April 30, 2025

In 2000, Isomers Skincare integrated Matrixyl® peptides into our product line-up to help support our customers’ anti-aging skincare efforts. In fact, we worked with Sederma to launch the ingredient Matrixyl® 3000 (inspired by the Nimbus Broom from Harry Potter!). While there are many versions of Matrixyl® on the market, the original formulation has proven time and again to be effective in reducing visible signs of aging!

Below, we’ll discuss what Matrixyl® is, how it works, and how you can work this powerful compound into your daily skincare routine. Keep reading! 

What Is Matrixyl®?

Matrixyl® is a synthetic peptide designed to promote skin regeneration and healing. This powerful compound stimulates collagen in the skin, which plays a crucial role in maintaining its structure, elasticity, and firmness. 

Proudly, Isomers Skincare is one of the only companies authorized to use all four forms of Matrixyl® in our product line-up, including:

  • Matrixyl® (Palmitoyl Pentapeptide-4)
  • Matrixyl 3000 (Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7)
  • Matrixyl Synthe'6 (Palmitoyl Tripeptide-38)
  • Matrixyl® Morphomics (N-Prolyl Palmitoyl Tripeptide-56 Acetate)

Matrixyl® peptides are great for supporting anti-aging, as they help reduce the appearance of wrinkles and fine lines, promote skin repair and healing, and fade dark spots on the skin.

Matrixyl® Morphomics (N-Prolyl Palmitoyl Tripeptide-56 Acetate)How Matrixyl® Peptides Work

Matrixyl® peptides encourage the skin to rebuild itself from the inside out. They mimic the skin’s natural peptides that are used during collagen synthesis and skin repair.

The peptides penetrate the outer layer (stratum corneum) of your skin to reach the middle layer of your skin (also known as the dermis). This is the area that contains your skin’s collagen and elastic tissue. 

Once the peptides reach the dermis, they stimulate fibroblast cells, which produce more collagen and elastin, the two key elements that maintain skin firmness and pliability.

With regular application, Matrixyl® will work its magic over your skin and stimulate its natural repair process, slowly reducing the effects of aging and offering a smoother and suppler appearance!

Matrixyl®-4 Products from Isomer’s Skincare

We have three products featured in our Matrixyl® Collection: the Matrixyl-4 Collagen Peptide Cream, the Matrixyl-4 Collagen Peptide Serum, and the Matrixyl Collagen Peptide Body Cream. These products are formulated to help boost collagen production and hydration and provide your skin with a smooth and firm look. Here are a few other benefits of these products:

Matrixyl®-4 Collagen Peptide Cream 

  • Helps soften the appearance of visible effects of environmental stress
  • Moisturizes the skin to maintain a soft and supple feeling
  • Promotes skin elasticity

Matrixyl®-4 Collagen Peptide Serum

  • Softens the appearance of fine lines and wrinkles
  • Creates a plump and hydrated appearance
  • Helps boost the firmness and elasticity of your skin
  • Stimulates lasting hydration

For the best results, pair our Matrixyl®-4 cream and serum together in your skincare routine. The serum provides a more concentrated dose, while the cream acts like a sealant, providing a slow and steady release. It's like pouring coffee into a travel mug—you need to add a tight lid to keep it fresh!

Matrixyl® Collagen Peptide Body Cream

  • Promotes skin elasticity and resilience
  • Helps even the skin tone by softening the appearance of scars and stretch marks
  • Smooths the appearance of fine lines and wrinkles
  • Offers intense hydration and locks in moisture

Things to Keep in Mind When Applying Matrixyl®

Do a patch test before using the product on your full face. Make sure it doesn’t irritate your skin and that you don’t experience any negative effects or allergic reactions. If you’re in the clear, feel free to start using it regularly!

UV protection is a non-negotiable for healthy and vibrant skin. Pair the Matrixyl®-4 cream and serum with a broad-spectrum sunscreen for enhanced skin protection.

Don’t expect instant results. Even the best products don’t change your skin overnight. It may take several weeks to a month before you see a significant change, but don't give up—consistency is key!

Embrace Anti-Aging with Isomers Skincare

Since 1988, Isomers Skincare has been challenging the beauty industry norms in our products with our results-driven, scientific approach to skincare. We focus on formulating products that target skin issues at a cellular level, including our Matrixyl® Collection for anti-aging. 

Visit our Shop to learn more about our Matrixyl® Collection and read the many positive reviews from our customers!